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ToxMystery, a game about chemicals in the household, will be retired on December 31, 2018. The game was built in the Adobe Flash, a format not supported on tablets, most Web browsers, and other educational devices. Although the game has provided years of fun and entertainment, we have decided to retire this resource. Please visit NIEHS and EPA for learning activities about chemicals and environmental health.

About ToxMystery

ToxMystery was created by the United States National Library of Medicine to help children from 7-11 years old learn about household chemical hazards. Toxie the Cat helps kids find the hazards hidden in each room and offers hints when needed. When all the risky spots in the house have been discovered, Toxie dances and celebrates and players can print a personalized certificate of completion. ToxMystery has been usability tested by kids and educators, receiving high grades by all.

ToxMystery is available in English and Spanish. Players can toggle between the languages without losing their place in the game, extending the game to language classes. ToxMystery not only educates young learners but provides parents and teachers with resources on environmental health. Parents can click on the "Parent Resources" or "Para los padres" tabs to find links to U.S. government and non-profit organization Web sites about everyday environmental hazards. The "For Teachers" or "Para maestros" pages contain 3 lesson plans with student worksheets and activities that use ToxMystery to explore common household chemical hazards. ToxMystery lesson plans were written using the National Science Educational Standards.

Poison Help Logo

If you think someone has been poisoned, call your poison center right away at 1-800-222-1222.




What do I need to run ToxMystery?

Online Version

  • The latest version of Internet Explorer, Mozilla Firefox, Opera or Safari is recommended
  • Macintosh or PC platform with a minimum of 125 megabytes of hard disk space
  • The latest free Flash Player
  • Free Adobe Reader
  • High speed internet connection

CD-ROM Version

  • MAC or PC platform with a minimum of 125 megabytes of hard disk space
  • CD-ROM drive - Internal or External

What does ToxMystery cost?

ToxMystery is free. Like all of the National Library of Medicine resources, ToxMystery is available for use by everyone with access to the Internet. If you don’t have access to the Internet you can request a ToxMystery CD.

How do I get ToxMystery?

ToxMystery is free on the Internet at: http://toxmystery.nlm.nih.gov. ToxMystery is also available on CD free of charge. Contact the Office of Communications and Public Liaison at publicinfo@nlm.nih.gov or 301-496-6308 to request a copy. The CD is in both English and Spanish.

How do I give you feedback or get answers to technical questions?

You can contact us at tehip@teh.nlm.nih.gov

I use a screen reader. Can I play ToxMystery?

At present, you cannot play the ToxMystery multimedia activity using a screen reader. We have provided a screen reader compatible text version with all of the information in the multimedia version.

Does ToxMystery save information about me?

ToxMystery does not save information about your visit. Please read our privacy policy for more information.

I'm a teacher. How can I use ToxMystery in my classroom?

ToxMystery has lesson plans with student worksheets and activities that use the game to explore common household chemical hazards. The materials are available in English and Spanish. The lesson plans were written using the National Science Educational Standards. Go to to the Teacher Resource page.

Check out Tox Town for teaching materials on environmental health for high school students.

Does ToxMystery have information for Parents?

The Parent Resources page has links to government and non-profit organization Web sites that provide in-depth information about common household and environmental risks. Go to Parent Resource page.

Can I add a link to ToxMystery on my web site?

We encourage you to link to ToxMystery. The address to use is http://toxmystery.nlm.nih.gov.

Promotional Material

Wall Paper

ToxMystery Wall paper

Instructions: Choose a wallpaper and then click on the image size matching your resolution.
When the image is displayed, right click on the image and select "Set as Wallpaper" or " Set as Background"

ToxMystert Wall Paper 3

800 x 600 pixels
1024 x 768 pixels
1280 x 1024 pixels

Clip Art

Clip Art

You may use ToxMystery images for creating links from your Web site or for training and publicity.


ToxMystery Garage

ToxMystery garage scene - a garage with a red car and a grey tabby cat sitting on the car

Cut and Paste code

<a href="http://toxmystery.nlm.nih.gov"><img src="http://toxmystery.distinctstudios.com/images/TM_2_150x136.gif width="150" height="136" alt="ToxMystery garage scene - a garage with a red car and a grey tabby cat sitting on the car"></a>


ToxMystery House

ToxMystery house - a two story white house with a grey tabby cat sitting by the front door

Cut and Paste Code

<a href="http://toxmystery.nlm.nih.gov"><image src="http://toxmystery.distinctstudios.com/images/TM_3_150x130.gif width="150" height="136" alt="ToxMystery house - a two story white house with a grey tabby cat sitting by the front door"></a>


Dancing Toxie

ToxMystery the cat- a grey tabby cat dancing

Cut and Paste Code

<a href ="http://toxmystery.nlm.nih.gov"><img src="http://toxmystery.distinctstudios.com/images/TM_125x125.gif width="125" height="125" alt="ToxMystery the cat- a grey tabby cat dancing"></a>"></a>


Toxie Peeking Out

Toxie the cat - a closeup of a grey tabby cat's face

Cut and Paste Code

<a href="http://toxmystery.nlm.nih.gov"><img src="http://toxmystery.distinctstudios.com/images/TM_150x135.gif width="150" height="136" alt="Toxie the cat - a closeup of a grey tabby cat's face"></a>